Melatonin is a hormone found naturally in the body. Some people take melatonin by mouth to adjust the body’s internal clock. Melatonin is most commonly used for insomnia and improving sleep in different conditions. For example, it is used for jet lag, for adjusting sleep-wake cycles in people whose daily work schedule changes (shift-work disorder), and for helping people establish a day and night cycle.  Melatonin’s main job in the body is to regulate night and day cycles or sleep-wake cycles. Darkness causes the body to produce more melatonin, which signals the body to prepare for sleep. Light decreases melatonin production and signals the body to prepare for being awake. Some people who have trouble sleeping have low levels of melatonin. It is thought that adding melatonin from supplements might help them sleep.  For trouble falling asleep at a conventional bedtime (delayed sleep phase syndrome): 0.3 to 5 mg of melatonin daily for up to 9 months has been used.
For sleep disturbance caused by certain blood pressure medicine (beta blocker-induced insomnia): 2.5 mg of melatonin taken daily for up to 4 weeks has been used. Single doses of 5 mg of melatonin have also been used.
For endometriosis: 10 mg of melatonin daily for 8 weeks has been used.
For high blood pressure: 2-3 mg of controlled-release melatonin daily for 4 weeks has been used.
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