Otrivine Adult Nasal Drops
Xylometazoline Hydrochloride 0.1% w/v
For excipients see 6.1.
Nasal drops, solution
The product is a clear, colourless solution.
For the symptomatic relief of nasal congestion, perennial and allergic rhinitis (including hay fever), sinusitis.
Adults and elderly (all indications): 2 or 3 drops in each nostril up to 3 times daily. Do not exceed 3 applications daily into each nostril.
The drops are suitable for children over 12 years of age. The recommended dose should not be exceeded, especially in children and the elderly.
Route of administration: Nasal use.
Known hypersensitivity to Otrivine
Patients with trans-sphenoidal hypophysectomy or surgery exposing the dura mater
Narrow-angle glaucoma
Rhinitis sicca or atrophic rhinitis.
Otrivine 0.1% is contraindicated in children aged less than 12 years
People with phaeochromocytoma or prostatic hypertrophy or receiving monoamine oxidase inhibitors (MAOI) treatment or who have received them in the last two weeks.
Patients are advised not to take decongestants for more than seven consecutive days. Prolonged or excessive use may cause rebound congestion and/or atrophy of the nasal mucosa.
Otrivine, like other preparations belonging to the same class of active substances, should be used only with caution in patients showing a strong reaction to sympathomimetic agents as evidenced by signs of insomnia, dizziness, tremor, cardiac arrhythmias or elevated blood pressure.
Caution is recommended in patients with hypertension, cardiovascular disease, hyperthyroidism or diabetes mellitus.
Patients with long QT syndrome treated with xylometazoline may be at increased risk of serious ventricular arrhythmias.
Keep medicines out of the sight and reach of children
Information concerning excipients
Otrivine contains benzalkonium chloride. This may cause irritation of the nasal mucosa.